Paracetamol/Acetaminophen/Panadol/Calpol - Indications, Contraindications, Caution and Side Effects
#CreatingForIndia #PCM(Acetaminophen) #mechanism of action #dosages #availability #Indications #Contraindications #Caution #Side effects 00:00 - 00:27 - Introduction 00:28 - 01:05 - Mechanism of action 01:06 - 01:48 - Availability 01:49 - 02:34 - Indications And Dosages 02:35 - 02:56 - Cautions 02:57 - 03:20 - Side Effects #PARACETAMOL(Acetaminophen) #Pharmacologic class: Synthetic nonopioid p-aminophenol derivative #Therapeutic class: Analgesic, antipyretic #Pregnancy risk category B #MECHANISM OF ACTION Unclear. #Pain relief may result from inhibition of prostaglandin synthesis in CNS, with subsequent blockage of pain impulses. #Fever reduction may result from vasodilation and increased peripheral blood flow in hypothalamus, which dissipates heat and lowers body temperature. #AVAILABILITY #Caplets (extra-strength): 500 mg Caplets, capsules: 160 mg, 500 mg, 650 mg (extended-release) #Drops: 100 mg/ml #Elixir: 80 mg/2.5 ml, 80 mg/5 ml, 120 mg/5 ml, 160 mg/5 ml #Gelcaps: 500 mg #Liquid: 160 mg/5 ml, 500 mg/15 ml #Solution: 80 mg/1.66 ml, 100 mg/1 ml, 120 mg/2.5 ml, 160 mg/5 ml, 167 mg/5 ml #Suppositories: 80 mg, 120 mg, 125 mg, 300 mg, 325 mg, 650 mg #Suspension: 32 mg/ml, 160 mg/5 ml Syrup: 160 mg/5 ml #Tablets (chewable): 80 mg, 160 mg Tablets (extended-release): 160 mg, 325 mg, 500 mg, 650 mg Tablets (film-coated): 160 mg, 325 mg, 500 mg #INDICATIONS AND #DOSAGES ➣ Mild to moderate pain caused by headache, muscle ache, backache, minor arthritis, common cold, toothache, or menstrual cramps or fever. Adults and children age 12 and older: 325 to 650 mg P.O. q 4 to 6 hours, or 1,000 mg three or four times daily. Or two extended-release caplets or tablets P.O. q 8 hours, to a maximum dosage of 4,000 mg/day. Or 650 mg P.R. q 4 to 6 hours, to a maximum dosage of 4,000 mg/day. Or, two extra-strength caplets q 6 hours, to a maximum dosage of six caplets/day. #DOSAGE #Dosage adjustment #Renal or hepatic impairment #Contraindications: #Hypersensitivity to drug #Precautions #Use cautiously in: Anaemia, hepatic or renal elderly patients pregnant or breastfeeding patients children younger than age 2. #SIDE EFFECTS Hematologic: Thrombocytopenia, Haemolytic anaemia, neutropenia, leukopenia, pancytopenia. Hepatic: jaundice, hepatotoxicity Metabolic: hypoglycaemic coma Skin: rash, urticaria Other: hypersensitivity reactions (such as fever) paracetamol,paracetamol overdose,paracetamol toxicity,how to use paracetamol,paracetemol,paracetamol poisoning,paracetamol side effect,paracetamol side effects,#paracetamol,paracetamol use,paracetamol dose,paracetamol uses,paracetamol news,paracetamol liver,paracetamol tablet,paracetamol dosage,paracetamol in pain,paracetamol effects,paracetamol tablets,paracetamol dangers,paracetamol for kids,paracetamol and adhd,waar is de paracetamol Follow us on https://www.mbbspedia.com https://www.facebook.com/ClinicalMaster https://www.facebook.com/groups/ClinicalMaster #ClinicalKnowledgeAndMedicine #mbbspedia
#CreatingForIndia #PCM(Acetaminophen) #mechanism of action #dosages #availability #Indications #Contraindications #Caution #Side effects 00:00 - 00:27 - Introduction 00:28 - 01:05 - Mechanism of action 01:06 - 01:48 - Availability 01:49 - 02:34 - Indications And Dosages 02:35 - 02:56 - Cautions 02:57 - 03:20 - Side Effects #PARACETAMOL(Acetaminophen) #Pharmacologic class: Synthetic nonopioid p-aminophenol derivative #Therapeutic class: Analgesic, antipyretic #Pregnancy risk category B #MECHANISM OF ACTION Unclear. #Pain relief may result from inhibition of prostaglandin synthesis in CNS, with subsequent blockage of pain impulses. #Fever reduction may result from vasodilation and increased peripheral blood flow in hypothalamus, which dissipates heat and lowers body temperature. #AVAILABILITY #Caplets (extra-strength): 500 mg Caplets, capsules: 160 mg, 500 mg, 650 mg (extended-release) #Drops: 100 mg/ml #Elixir: 80 mg/2.5 ml, 80 mg/5 ml, 120 mg/5 ml, 160 mg/5 ml #Gelcaps: 500 mg #Liquid: 160 mg/5 ml, 500 mg/15 ml #Solution: 80 mg/1.66 ml, 100 mg/1 ml, 120 mg/2.5 ml, 160 mg/5 ml, 167 mg/5 ml #Suppositories: 80 mg, 120 mg, 125 mg, 300 mg, 325 mg, 650 mg #Suspension: 32 mg/ml, 160 mg/5 ml Syrup: 160 mg/5 ml #Tablets (chewable): 80 mg, 160 mg Tablets (extended-release): 160 mg, 325 mg, 500 mg, 650 mg Tablets (film-coated): 160 mg, 325 mg, 500 mg #INDICATIONS AND #DOSAGES ➣ Mild to moderate pain caused by headache, muscle ache, backache, minor arthritis, common cold, toothache, or menstrual cramps or fever. Adults and children age 12 and older: 325 to 650 mg P.O. q 4 to 6 hours, or 1,000 mg three or four times daily. Or two extended-release caplets or tablets P.O. q 8 hours, to a maximum dosage of 4,000 mg/day. Or 650 mg P.R. q 4 to 6 hours, to a maximum dosage of 4,000 mg/day. Or, two extra-strength caplets q 6 hours, to a maximum dosage of six caplets/day. #DOSAGE #Dosage adjustment #Renal or hepatic impairment #Contraindications: #Hypersensitivity to drug #Precautions #Use cautiously in: Anaemia, hepatic or renal elderly patients pregnant or breastfeeding patients children younger than age 2. #SIDE EFFECTS Hematologic: Thrombocytopenia, Haemolytic anaemia, neutropenia, leukopenia, pancytopenia. Hepatic: jaundice, hepatotoxicity Metabolic: hypoglycaemic coma Skin: rash, urticaria Other: hypersensitivity reactions (such as fever) paracetamol,paracetamol overdose,paracetamol toxicity,how to use paracetamol,paracetemol,paracetamol poisoning,paracetamol side effect,paracetamol side effects,#paracetamol,paracetamol use,paracetamol dose,paracetamol uses,paracetamol news,paracetamol liver,paracetamol tablet,paracetamol dosage,paracetamol in pain,paracetamol effects,paracetamol tablets,paracetamol dangers,paracetamol for kids,paracetamol and adhd,waar is de paracetamol Follow us on https://www.mbbspedia.com https://www.facebook.com/ClinicalMaster https://www.facebook.com/groups/ClinicalMaster #ClinicalKnowledgeAndMedicine #mbbspedia